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10 Best MAT Programs in San Francisco, CA (2026)

We list 18 mat programs in San Francisco, CA, based on SAMHSA's FindTreatment.gov data. Compare services, insurance accepted and accreditation, or call for free help choosing.

  • 18Treatment facilities
  • 4Offer detox
  • 7Inpatient / residential
  • 10Accept Medicaid

Medication-Assisted Treatment (MAT): the basics

Medication-assisted treatment (MAT) uses FDA-approved medications, usually alongside counseling, to treat opioid and alcohol use disorders. For opioids, the options are buprenorphine (including Suboxone), methadone and naltrexone. These medications ease cravings and withdrawal, help prevent a return to use and lower overdose risk. Search below to find MAT and Suboxone clinics near you. Read the full guide →

2026 rankings

Top 10 MAT programs in San Francisco, CA

Ranked by the StartDrugRehab Score: accreditation, levels of care, patient ratings and payment options. Featured or claimed status never affects rank. How we rank

  1. Veterans Affairs Medical Center – Addiction Recovery Treatment Services

    San Francisco, CA

    8.1ExcellentStartDrugRehab Score 8.1 out of 10
    4.3Google451 reviews

    Best for: Veterans (VA care)Joint CommissionCARF

    Why it made our list: Joint Commission and CARF accredited; offers detox, IOP, outpatient care, and MAT.

    View details
  2. San Francisco VA Downtown Clinic

    San Francisco, CA

    7.3Very goodStartDrugRehab Score 7.3 out of 10
    4.3Google22 reviews

    Best for: Veterans (VA care)Joint Commission

    Why it made our list: Joint Commission accredited; offers outpatient care, MAT, and dual diagnosis care; accepts private insurance.

    View details
  3. HealthRIGHT 360 – Women’s Hope

    San Francisco, CA

    7.3Very goodStartDrugRehab Score 7.3 out of 10
    4.4Google5 reviews

    Best for: Residential treatmentCARF

    Why it made our list: CARF accredited; offers residential care, MAT, and dual diagnosis care; accepts Medicaid and Medicare.

    View details
  4. Foundations San Francisco

    San Francisco, CA

    7.2Very goodStartDrugRehab Score 7.2 out of 10
    3.2Google17 reviews

    Best for: Intensive outpatient careJoint Commission

    Why it made our list: Joint Commission accredited; offers PHP, IOP, MAT, and dual diagnosis care; accepts private insurance, TRICARE, and self-pay.

    View details
  5. Bayview Hunters Point Foundation – Substance Use Disorder Programs

    San Francisco, CA

    7.2Very goodStartDrugRehab Score 7.2 out of 10
    4.3Google12 reviews

    Best for: Methadone treatmentCARF

    Why it made our list: CARF accredited; offers outpatient care, MAT, and dual diagnosis care; accepts Medicare and self-pay.

    View details
  6. Addiction Research and Treatment Inc (ART)

    San Francisco, CA

    7.2Very goodStartDrugRehab Score 7.2 out of 10

    Best for: Methadone treatmentCARF

    Why it made our list: CARF accredited; offers outpatient care and MAT; accepts private insurance, Medicaid, and Medicare.

    View details
  7. Friendship House – Association of American Indians

    San Francisco, CA

    7.1Very goodStartDrugRehab Score 7.1 out of 10
    3.4Google28 reviews

    Best for: Residential treatmentCARF

    Why it made our list: CARF accredited; offers residential care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.

    View details
  8. Fort Help Mission Inc

    San Francisco, CA

    6.9GoodStartDrugRehab Score 6.9 out of 10
    5.0Google11 reviews

    Best for: Supervised detoxCOA

    Why it made our list: COA accredited; offers detox, outpatient care, MAT, and dual diagnosis care; accepts Medicaid, Medicare, and self-pay.

    View details
  9. San Francisco General Hospital – Opiate Treatment Outpatient Program

    San Francisco, CA

    6.5GoodStartDrugRehab Score 6.5 out of 10

    Best for: Methadone treatmentCARF

    Why it made our list: CARF accredited; offers MAT; accepts Medicaid.

    View details
  10. Mission Council Family Day Treatment

    San Francisco, CA

    6.3GoodStartDrugRehab Score 6.3 out of 10

    Best for: Intensive outpatient care

    Why it made our list: Offers IOP, outpatient care, MAT, and dual diagnosis care; accepts Medicaid and Medicare.

    View details

See the best rehab centers in San Francisco, CA →

All MAT programs in San Francisco, CA

7.1Very goodStartDrugRehab Score 7.1 out of 10
3.4Google28 reviews

CARF accredited

Setting
In/Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Inpatient / Residential
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Medicare · Private insurance +3 more

“Get help” calls our free helpline, not this facility.

7.2Very goodStartDrugRehab Score 7.2 out of 10

CARF accredited

Setting
In/Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Inpatient / Residential
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Medicare · State-funded

“Get help” calls our free helpline, not this facility.

HealthRIGHT 360 – Women’s Hope

San Francisco, CA 94110

7.3Very goodStartDrugRehab Score 7.3 out of 10
4.4Google5 reviews

CARF accredited

Setting
In/Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Inpatient / Residential
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Medicare · State-funded

“Get help” calls our free helpline, not this facility.

6.0GoodStartDrugRehab Score 6.0 out of 10
5.0Google1 review
Setting
In/Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Detox
  • Inpatient / Residential
  • Medication-Assisted Treatment
  • +1 more

Payment accepted

Private insurance · Self-pay

“Get help” calls our free helpline, not this facility.

7.2Very goodStartDrugRehab Score 7.2 out of 10

CARF accredited

Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Methadone Clinic
  • +1 more

Payment accepted

Medicaid · Medicare · Private insurance +3 more

“Get help” calls our free helpline, not this facility.

Foundations San Francisco

San Francisco, CA 94111

7.2Very goodStartDrugRehab Score 7.2 out of 10
3.2Google17 reviews

Joint Commission accredited

Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Partial Hospitalization
  • Intensive Outpatient
  • Medication-Assisted Treatment
  • +2 more

Payment accepted

Private insurance · TRICARE · Self-pay

“Get help” calls our free helpline, not this facility.

San Francisco VA Downtown Clinic

San Francisco, CA 94107

7.3Very goodStartDrugRehab Score 7.3 out of 10
4.3Google22 reviews

Joint Commission accredited

Setting
Outpatient
Operator
Public
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Private insurance · State-funded

“Get help” calls our free helpline, not this facility.

7.2Very goodStartDrugRehab Score 7.2 out of 10
4.3Google12 reviews

CARF accredited

Setting
Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Methadone Clinic
  • +2 more

Payment accepted

Medicare · Self-pay · State-funded

“Get help” calls our free helpline, not this facility.

Epiphany Residential

San Francisco, CA 94118

6.0GoodStartDrugRehab Score 6.0 out of 10
3.9Google15 reviews
Setting
In/Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Inpatient / Residential
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Medicare · Sliding scale +1 more

“Get help” calls our free helpline, not this facility.

Fort Help Mission Inc

San Francisco, CA 94110

6.9GoodStartDrugRehab Score 6.9 out of 10
5.0Google11 reviews

COA accredited

Setting
In/Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Detox
  • Outpatient
  • Medication-Assisted Treatment
  • +2 more

Payment accepted

Medicaid · Medicare · Self-pay

“Get help” calls our free helpline, not this facility.

5.5FairStartDrugRehab Score 5.5 out of 10
5.0Google3 reviews
Setting
Inpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Inpatient / Residential
  • Hospital Inpatient
  • Medication-Assisted Treatment

“Get help” calls our free helpline, not this facility.

5.8FairStartDrugRehab Score 5.8 out of 10
Setting
Outpatient
Operator
Public
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

State-funded

“Get help” calls our free helpline, not this facility.

Homeless Childrens Network – Kupona

San Francisco, CA 94115

5.4FairStartDrugRehab Score 5.4 out of 10
3.4Google750 reviews
Setting
Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Intensive Outpatient
  • Outpatient
  • Medication-Assisted Treatment
  • +1 more

Payment accepted

Medicaid

“Get help” calls our free helpline, not this facility.

Mission Council Family Day Treatment

San Francisco, CA 94110

6.3GoodStartDrugRehab Score 6.3 out of 10
Setting
Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Intensive Outpatient
  • Outpatient
  • Medication-Assisted Treatment
  • +2 more

Payment accepted

Medicaid · Medicare · State-funded

“Get help” calls our free helpline, not this facility.

More options in San Francisco, CA

MAT Programs in other California cities

Frequently asked questions

How many mat programs are in San Francisco, CA?

We list 18 mat programs in San Francisco, CA, based on SAMHSA's FindTreatment.gov data (updated October 2026).

How do I choose the right program?

Look for state licensing and accreditation (The Joint Commission or CARF), the right level of care for your needs, evidence-based therapies, and insurance compatibility. Read our guide to choosing a rehab or call (833) 589-6933 to talk it through.

Will my insurance cover treatment?

Most private plans and Medicaid cover substance use treatment when it's medically necessary, but benefits vary by plan and network. Call (833) 589-6933 for a free, confidential benefits check.

Source: SAMHSA FindTreatment.gov, data updated October 2026. Listings are not endorsements.