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7 Best MAT Programs in Greenville, NC (2026)

We list 7 mat programs in Greenville, NC, based on SAMHSA's FindTreatment.gov data. Compare services, insurance accepted and accreditation, or call for free help choosing.

  • 7Treatment facilities
  • 0Offer detox
  • 1Inpatient / residential
  • 6Accept Medicaid

Medication-Assisted Treatment (MAT): the basics

Medication-assisted treatment (MAT) uses FDA-approved medications, usually alongside counseling, to treat opioid and alcohol use disorders. For opioids, the options are buprenorphine (including Suboxone), methadone and naltrexone. These medications ease cravings and withdrawal, help prevent a return to use and lower overdose risk. Search below to find MAT and Suboxone clinics near you. Read the full guide →

2026 rankings

Top 7 MAT programs in Greenville, NC

Ranked by the StartDrugRehab Score: accreditation, levels of care, patient ratings and payment options. Featured or claimed status never affects rank. How we rank

  1. Pathways to Life Inc

    Greenville, NC

    7.9Very goodStartDrugRehab Score 7.9 out of 10
    4.4Google50 reviews

    Best for: Intensive outpatient careCARF

    Why it made our list: CARF accredited; offers IOP, outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.

    View details
  2. Easterseals – Greenville OTP

    Greenville, NC

    7.3Very goodStartDrugRehab Score 7.3 out of 10
    2.7Google58 reviews

    Best for: Methadone treatmentCARF

    Why it made our list: CARF accredited; offers PHP, IOP, outpatient care, and MAT; accepts private insurance, Medicaid, and Medicare.

    View details
  3. Easterseals PORT Health Services – Greenville Clinic

    Greenville, NC

    7.0Very goodStartDrugRehab Score 7.0 out of 10
    2.7Google58 reviews

    Best for: Intensive outpatient careCARF

    Why it made our list: CARF accredited; offers IOP, outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.

    View details
  4. Greenville Treatment Center LLC

    Greenville, NC

    6.7GoodStartDrugRehab Score 6.7 out of 10
    3.8Google20 reviews

    Best for: Methadone treatmentCARF

    Why it made our list: CARF accredited; offers outpatient care and MAT; accepts Medicaid and self-pay.

    View details
  5. Durham VA Healthcare System – Greenville Healthcare Center

    Greenville, NC

    6.6GoodStartDrugRehab Score 6.6 out of 10
    3.6Google177 reviews

    Best for: Veterans (VA care)Joint Commission

    Why it made our list: Joint Commission accredited; offers outpatient care, MAT, and dual diagnosis care; accepts TRICARE.

    View details
  6. Easterseals PORT Health – PORT Program

    Greenville, NC

    6.2GoodStartDrugRehab Score 6.2 out of 10

    Best for: Residential treatment

    Why it made our list: Offers residential care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and TRICARE.

    View details
  7. Eastern Physical Medicine and – Rehabilitation PLLC

    Greenville, NC

    5.7FairStartDrugRehab Score 5.7 out of 10
    3.5Google48 reviews

    Best for: Outpatient care with MAT

    Why it made our list: Offers outpatient care and MAT; accepts private insurance, Medicaid, and Medicare.

    View details

See the best rehab centers in Greenville, NC →

All MAT programs in Greenville, NC

Easterseals – Greenville OTP

Greenville, NC 27834

7.3Very goodStartDrugRehab Score 7.3 out of 10
2.7Google58 reviews

CARF accredited

Setting
Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Partial Hospitalization
  • Intensive Outpatient
  • Outpatient
  • +4 more

Payment accepted

Medicaid · Medicare · Private insurance +3 more

“Get help” calls our free helpline, not this facility.

7.0Very goodStartDrugRehab Score 7.0 out of 10
2.7Google58 reviews

CARF accredited

Setting
Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Intensive Outpatient
  • Outpatient
  • Medication-Assisted Treatment
  • +2 more

Payment accepted

Medicaid · Medicare · Private insurance +3 more

“Get help” calls our free helpline, not this facility.

Pathways to Life Inc

Greenville, NC 27858

7.9Very goodStartDrugRehab Score 7.9 out of 10
4.4Google50 reviews

CARF accredited

Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Intensive Outpatient
  • Outpatient
  • Medication-Assisted Treatment
  • +2 more

Payment accepted

Medicaid · Medicare · Private insurance +2 more

“Get help” calls our free helpline, not this facility.

6.6GoodStartDrugRehab Score 6.6 out of 10
3.6Google177 reviews

Joint Commission accredited

Setting
Outpatient
Operator
Public
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

TRICARE

“Get help” calls our free helpline, not this facility.

6.2GoodStartDrugRehab Score 6.2 out of 10
Setting
In/Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Inpatient / Residential
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Private insurance · TRICARE +2 more

“Get help” calls our free helpline, not this facility.

Greenville Treatment Center LLC

Greenville, NC 27834

6.7GoodStartDrugRehab Score 6.7 out of 10
3.8Google20 reviews

CARF accredited

Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Methadone Clinic
  • +1 more

Payment accepted

Medicaid · Self-pay · State-funded

“Get help” calls our free helpline, not this facility.

5.7FairStartDrugRehab Score 5.7 out of 10
3.5Google48 reviews
Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment

Payment accepted

Medicaid · Medicare · Private insurance +2 more

“Get help” calls our free helpline, not this facility.

More options in Greenville, NC

MAT Programs in other North Carolina cities

Frequently asked questions

How many mat programs are in Greenville, NC?

We list 7 mat programs in Greenville, NC, based on SAMHSA's FindTreatment.gov data (updated October 2026).

How do I choose the right program?

Look for state licensing and accreditation (The Joint Commission or CARF), the right level of care for your needs, evidence-based therapies, and insurance compatibility. Read our guide to choosing a rehab or call (833) 589-6933 to talk it through.

Will my insurance cover treatment?

Most private plans and Medicaid cover substance use treatment when it's medically necessary, but benefits vary by plan and network. Call (833) 589-6933 for a free, confidential benefits check.

Source: SAMHSA FindTreatment.gov, data updated October 2026. Listings are not endorsements.