We list 4 dual diagnosis treatment centers in Sioux Falls, SD, based on SAMHSA's FindTreatment.gov data. Compare services, insurance accepted and accreditation, or call for free help choosing.
Dual Diagnosis: the basics
Dual diagnosis treatment is care for people who have both a substance use disorder and a mental health condition, such as depression, anxiety, PTSD or bipolar disorder. The best programs treat both conditions at the same time with one coordinated team, combining therapy, psychiatric care and, when needed, medication for addiction. Read the full guide →
2026 rankings
Ranked by the StartDrugRehab Score: accreditation, levels of care, patient ratings and payment options. Featured or claimed status never affects rank. How we rank
Best for: Intensive outpatient careJoint Commission
Why it made our list: Joint Commission accredited; offers IOP, outpatient care, and dual diagnosis care; accepts private insurance, Medicare, and TRICARE.
Best for: Residential treatmentCOA
Why it made our list: COA accredited; offers residential care, IOP, outpatient care, and MAT; accepts private insurance, Medicaid, and TRICARE.
Best for: Intensive outpatient careCARF
Why it made our list: CARF accredited; offers IOP, outpatient care, and dual diagnosis care; accepts Medicaid and self-pay.
Best for: Residential treatmentCARF
Why it made our list: CARF accredited; offers residential care and dual diagnosis care; accepts Medicaid and self-pay.
Sioux Falls, SD 57104
CARF accredited
Levels of care
Payment accepted
Medicaid · Self-pay · State-funded
“Get help” calls our free helpline, not this facility.
Sioux Falls, SD 57105
Joint Commission accredited
Levels of care
Payment accepted
Medicare · Private insurance · TRICARE +1 more
“Get help” calls our free helpline, not this facility.
Sioux Falls, SD 57105
COA accredited
Levels of care
Payment accepted
Medicaid · Private insurance · TRICARE +3 more
“Get help” calls our free helpline, not this facility.
Sioux Falls, SD 57104
CARF accredited
Levels of care
Payment accepted
Medicaid · Self-pay · State-funded
“Get help” calls our free helpline, not this facility.
We list 4 dual diagnosis treatment centers in Sioux Falls, SD, based on SAMHSA's FindTreatment.gov data (updated October 2026).
Look for state licensing and accreditation (The Joint Commission or CARF), the right level of care for your needs, evidence-based therapies, and insurance compatibility. Read our guide to choosing a rehab or call (833) 589-6933 to talk it through.
Most private plans and Medicaid cover substance use treatment when it's medically necessary, but benefits vary by plan and network. Call (833) 589-6933 for a free, confidential benefits check.
Source: SAMHSA FindTreatment.gov, data updated October 2026. Listings are not endorsements.
