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10 Best MAT Programs in Louisville, KY (2026)

We list 23 mat programs in Louisville, KY, based on SAMHSA's FindTreatment.gov data. Compare services, insurance accepted and accreditation, or call for free help choosing.

  • 23Treatment facilities
  • 6Offer detox
  • 5Inpatient / residential
  • 19Accept Medicaid

Medication-Assisted Treatment (MAT): the basics

Medication-assisted treatment (MAT) uses FDA-approved medications, usually alongside counseling, to treat opioid and alcohol use disorders. For opioids, the options are buprenorphine (including Suboxone), methadone and naltrexone. These medications ease cravings and withdrawal, help prevent a return to use and lower overdose risk. Search below to find MAT and Suboxone clinics near you. Read the full guide →

2026 rankings

Top 10 MAT programs in Louisville, KY

Ranked by the StartDrugRehab Score: accreditation, levels of care, patient ratings and payment options. Featured or claimed status never affects rank. How we rank

  1. Louisville Recovery Center – Tranquility Recovery Center

    Louisville, KY

    8.8ExcellentStartDrugRehab Score 8.8 out of 10
    5.0Google36 reviews

    Best for: Supervised detoxJoint Commission

    Why it made our list: Joint Commission accredited; offers detox, PHP, IOP, and outpatient care; accepts private insurance, Medicaid, and TRICARE.

    View details
  2. Veterans Affairs Medical Center – Substance Abuse Services

    Louisville, KY

    8.2ExcellentStartDrugRehab Score 8.2 out of 10
    4.1Google373 reviews

    Best for: Veterans (VA care)Joint CommissionCARF

    Why it made our list: Joint Commission and CARF accredited; offers detox, residential care, IOP, and outpatient care; accepts private insurance, TRICARE, and self-pay.

    View details
  3. Seven Counties Services – Addiction Recovery Center

    Louisville, KY

    8.0ExcellentStartDrugRehab Score 8.0 out of 10

    Best for: Residential treatmentJoint Commission

    Why it made our list: Joint Commission accredited; offers residential care, IOP, outpatient care, and MAT; accepts private insurance, Medicaid, and TRICARE.

    View details
  4. BrightView Health

    Louisville, KY

    7.9Very goodStartDrugRehab Score 7.9 out of 10
    4.2Google80 reviews

    Best for: Supervised detoxJoint Commission

    Why it made our list: Joint Commission accredited; offers detox, PHP, outpatient care, and MAT; accepts Medicaid, Medicare, and self-pay.

    View details
  5. Brook Hospital – Dupont

    Louisville, KY

    7.9Very goodStartDrugRehab Score 7.9 out of 10
    3.8Google379 reviews

    Best for: Supervised detoxJoint Commission

    Why it made our list: Joint Commission accredited; offers detox, PHP, IOP, and MAT; accepts private insurance, Medicaid, and Medicare.

    View details
  6. MedMark Treatment Center – Louisville

    Louisville, KY

    7.8Very goodStartDrugRehab Score 7.8 out of 10
    4.6Google34 reviews

    Best for: Methadone treatmentCARF

    Why it made our list: CARF accredited; offers outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.

    View details
  7. Behavioral Health Group – Louisville Treatment Center

    Louisville, KY

    7.8Very goodStartDrugRehab Score 7.8 out of 10
    4.0Google94 reviews

    Best for: Methadone treatmentJoint Commission

    Why it made our list: Joint Commission accredited; offers IOP, outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.

    View details
  8. Spero Health

    Louisville, KY

    7.7Very goodStartDrugRehab Score 7.7 out of 10
    4.5Google49 reviews

    Best for: Outpatient care with MATCARF

    Why it made our list: CARF accredited; offers outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.

    View details
  9. Volunteers of America Mid States – Freedom House 1 Residential IOP

    Louisville, KY

    7.6Very goodStartDrugRehab Score 7.6 out of 10
    4.3Google60 reviews

    Best for: Residential treatmentCARFCOA

    Why it made our list: CARF and COA accredited; offers residential care, MAT, and dual diagnosis care; accepts Medicaid, self-pay, and sliding-scale fees.

    View details
  10. VOA Addiction Recovery Services – Freedom House 3 Residential Services

    Louisville, KY

    7.5Very goodStartDrugRehab Score 7.5 out of 10
    5.0Google3 reviews

    Best for: Residential treatmentCARFCOA

    Why it made our list: CARF and COA accredited; offers residential care, MAT, and dual diagnosis care; accepts Medicaid, self-pay, and sliding-scale fees.

    View details

See the best rehab centers in Louisville, KY →

All MAT programs in Louisville, KY

8.2ExcellentStartDrugRehab Score 8.2 out of 10
4.1Google373 reviews

Joint Commission · CARF accredited

Setting
In/Outpatient
Operator
Public
MAT
Offered

Levels of care

  • Detox
  • Inpatient / Residential
  • Intensive Outpatient
  • +3 more

Payment accepted

Private insurance · TRICARE · Self-pay

“Get help” calls our free helpline, not this facility.

Brook Hospital – Dupont

Louisville, KY 40207

7.9Very goodStartDrugRehab Score 7.9 out of 10
3.8Google379 reviews

Joint Commission accredited

Setting
In/Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Detox
  • Hospital Inpatient
  • Partial Hospitalization
  • +3 more

Payment accepted

Medicaid · Medicare · Private insurance +2 more

“Get help” calls our free helpline, not this facility.

8.8ExcellentStartDrugRehab Score 8.8 out of 10
5.0Google36 reviews

Joint Commission accredited

Setting
In/Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Detox
  • Partial Hospitalization
  • Intensive Outpatient
  • +4 more

Payment accepted

Medicaid · Private insurance · TRICARE +2 more

“Get help” calls our free helpline, not this facility.

8.0ExcellentStartDrugRehab Score 8.0 out of 10

Joint Commission accredited

Setting
In/Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Inpatient / Residential
  • Intensive Outpatient
  • Outpatient
  • +3 more

Payment accepted

Medicaid · Private insurance · TRICARE +2 more

“Get help” calls our free helpline, not this facility.

UofL Health – Peace Hospital

Louisville, KY 40205

7.3Very goodStartDrugRehab Score 7.3 out of 10
2.0Google305 reviews

Joint Commission accredited

Setting
In/Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Detox
  • Hospital Inpatient
  • Partial Hospitalization
  • +4 more

Payment accepted

Medicaid · Medicare · Private insurance +2 more

“Get help” calls our free helpline, not this facility.

BrightView Health

Louisville, KY 40272

7.9Very goodStartDrugRehab Score 7.9 out of 10
4.2Google80 reviews

Joint Commission accredited

Setting
In/Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Detox
  • Partial Hospitalization
  • Outpatient
  • +4 more

Payment accepted

Medicaid · Medicare · Self-pay

“Get help” calls our free helpline, not this facility.

7.4Very goodStartDrugRehab Score 7.4 out of 10

Joint Commission accredited

Setting
In/Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Inpatient / Residential
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Private insurance · TRICARE +2 more

“Get help” calls our free helpline, not this facility.

7.8Very goodStartDrugRehab Score 7.8 out of 10
4.0Google94 reviews

Joint Commission accredited

Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Intensive Outpatient
  • Outpatient
  • Medication-Assisted Treatment
  • +3 more

Payment accepted

Medicaid · Medicare · Private insurance +3 more

“Get help” calls our free helpline, not this facility.

7.6Very goodStartDrugRehab Score 7.6 out of 10
4.3Google60 reviews

CARF · COA accredited

Setting
In/Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Inpatient / Residential
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Self-pay · Sliding scale

“Get help” calls our free helpline, not this facility.

Getwell Recovery

Louisville, KY 40203

6.5GoodStartDrugRehab Score 6.5 out of 10
1.6Google8 reviews

Joint Commission accredited

Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Methadone Clinic
  • +1 more

Payment accepted

Medicaid · Medicare · Private insurance +2 more

“Get help” calls our free helpline, not this facility.

7.2Very goodStartDrugRehab Score 7.2 out of 10

Joint Commission accredited

Setting
Outpatient
Operator
Public
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Private insurance · Self-pay

“Get help” calls our free helpline, not this facility.

7.0Very goodStartDrugRehab Score 7.0 out of 10
3.8Google57 reviews

Joint Commission accredited

Setting
Outpatient
Operator
Public
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Private insurance · Self-pay

“Get help” calls our free helpline, not this facility.

7.3Very goodStartDrugRehab Score 7.3 out of 10
4.3Google40 reviews

Joint Commission accredited

Setting
Outpatient
Operator
Public
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Private insurance · Self-pay

“Get help” calls our free helpline, not this facility.

7.8Very goodStartDrugRehab Score 7.8 out of 10
4.6Google34 reviews

CARF accredited

Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Methadone Clinic
  • +2 more

Payment accepted

Medicaid · Medicare · Private insurance +4 more

“Get help” calls our free helpline, not this facility.

Spero Health

Louisville, KY 40207

7.7Very goodStartDrugRehab Score 7.7 out of 10
4.5Google49 reviews

CARF accredited

Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Medicare · Private insurance +2 more

“Get help” calls our free helpline, not this facility.

AppleGate Recovery – Louisville

Louisville, KY 40243

6.9GoodStartDrugRehab Score 6.9 out of 10
4.6Google48 reviews
Setting
In/Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Detox
  • Outpatient
  • Medication-Assisted Treatment
  • +2 more

Payment accepted

Medicaid · Medicare · Private insurance +2 more

“Get help” calls our free helpline, not this facility.

CleanSlate Centers – Louisville

Louisville, KY 40202

7.2Very goodStartDrugRehab Score 7.2 out of 10

CARF accredited

Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Telehealth

Payment accepted

Medicaid · Medicare · Private insurance +2 more

“Get help” calls our free helpline, not this facility.

7.1Very goodStartDrugRehab Score 7.1 out of 10
4.3Google185 reviews

CARF accredited

Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Medication-Assisted Treatment
  • Methadone Clinic
  • Telehealth

Payment accepted

Medicaid · Medicare · Private insurance +2 more

“Get help” calls our free helpline, not this facility.

7.4Very goodStartDrugRehab Score 7.4 out of 10
4.0Google43 reviews

CARF · COA accredited

Setting
Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +2 more

Payment accepted

Medicaid · Self-pay · Sliding scale

“Get help” calls our free helpline, not this facility.

Nulease Medical Solutions

Louisville, KY 40219

7.3Very goodStartDrugRehab Score 7.3 out of 10
4.7Google175 reviews
Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Partial Hospitalization
  • Intensive Outpatient
  • Outpatient
  • +3 more

Payment accepted

Medicaid · Medicare · Private insurance +1 more

“Get help” calls our free helpline, not this facility.

Morton Center

Louisville, KY 40204

6.7GoodStartDrugRehab Score 6.7 out of 10
4.3Google51 reviews
Setting
Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Intensive Outpatient
  • Outpatient
  • Medication-Assisted Treatment
  • +2 more

Payment accepted

Medicaid · Medicare · Private insurance +3 more

“Get help” calls our free helpline, not this facility.

New Leaf Clinic

Louisville, KY 40203

6.3GoodStartDrugRehab Score 6.3 out of 10
4.2Google26 reviews
Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Intensive Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Medicare · Private insurance +1 more

“Get help” calls our free helpline, not this facility.

More options in Louisville, KY

MAT Programs in other Kentucky cities

Frequently asked questions

How many mat programs are in Louisville, KY?

We list 23 mat programs in Louisville, KY, based on SAMHSA's FindTreatment.gov data (updated October 2026).

How do I choose the right program?

Look for state licensing and accreditation (The Joint Commission or CARF), the right level of care for your needs, evidence-based therapies, and insurance compatibility. Read our guide to choosing a rehab or call (833) 589-6933 to talk it through.

Will my insurance cover treatment?

Most private plans and Medicaid cover substance use treatment when it's medically necessary, but benefits vary by plan and network. Call (833) 589-6933 for a free, confidential benefits check.

Source: SAMHSA FindTreatment.gov, data updated October 2026. Listings are not endorsements.