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5 Best MAT Programs in Owensboro, KY (2026)

We list 5 mat programs in Owensboro, KY, based on SAMHSA's FindTreatment.gov data. Compare services, insurance accepted and accreditation, or call for free help choosing.

  • 5Treatment facilities
  • 1Offer detox
  • 0Inpatient / residential
  • 5Accept Medicaid

Medication-Assisted Treatment (MAT): the basics

Medication-assisted treatment (MAT) uses FDA-approved medications, usually alongside counseling, to treat opioid and alcohol use disorders. For opioids, the options are buprenorphine (including Suboxone), methadone and naltrexone. These medications ease cravings and withdrawal, help prevent a return to use and lower overdose risk. Search below to find MAT and Suboxone clinics near you. Read the full guide →

2026 rankings

Top 5 MAT programs in Owensboro, KY

Ranked by the StartDrugRehab Score: accreditation, levels of care, patient ratings and payment options. Featured or claimed status never affects rank. How we rank

  1. Spero Health

    Owensboro, KY

    7.8Very goodStartDrugRehab Score 7.8 out of 10
    4.6Google46 reviews

    Best for: Outpatient care with MATCARF

    Why it made our list: CARF accredited; offers outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.

    View details
  2. TrueNorth Treatment Center

    Owensboro, KY

    7.8Very goodStartDrugRehab Score 7.8 out of 10
    3.3Google12 reviews

    Best for: Intensive outpatient careCARF

    Why it made our list: CARF accredited; offers PHP, IOP, outpatient care, and MAT; accepts private insurance, Medicaid, and Medicare.

    View details
  3. RiverValley Behavioral Health – Daviess County Outpatient Clinic

    Owensboro, KY

    7.3Very goodStartDrugRehab Score 7.3 out of 10
    2.4Google68 reviews

    Best for: Supervised detoxCARF

    Why it made our list: CARF accredited; offers detox, IOP, outpatient care, and MAT; accepts private insurance, Medicaid, and Medicare.

    View details
  4. CleanSlate Centers – Owensboro

    Owensboro, KY

    7.2Very goodStartDrugRehab Score 7.2 out of 10

    Best for: Outpatient care with MATCARF

    Why it made our list: CARF accredited; offers outpatient care and MAT; accepts private insurance, Medicaid, and Medicare.

    View details
  5. Mountain Comprehensive Care Center

    Owensboro, KY

    7.0Very goodStartDrugRehab Score 7.0 out of 10
    3.2Google11 reviews

    Best for: Intensive outpatient careCARF

    Why it made our list: CARF accredited; offers IOP, outpatient care, MAT, and dual diagnosis care; accepts Medicaid.

    View details

See the best rehab centers in Owensboro, KY →

All MAT programs in Owensboro, KY

TrueNorth Treatment Center

Owensboro, KY 42303

7.8Very goodStartDrugRehab Score 7.8 out of 10
3.3Google12 reviews

CARF accredited

Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Partial Hospitalization
  • Intensive Outpatient
  • Outpatient
  • +4 more

Payment accepted

Medicaid · Medicare · Private insurance +1 more

“Get help” calls our free helpline, not this facility.

Spero Health

Owensboro, KY 42303

7.8Very goodStartDrugRehab Score 7.8 out of 10
4.6Google46 reviews

CARF accredited

Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Medicare · Private insurance +2 more

“Get help” calls our free helpline, not this facility.

CleanSlate Centers – Owensboro

Owensboro, KY 42303

7.2Very goodStartDrugRehab Score 7.2 out of 10

CARF accredited

Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Telehealth

Payment accepted

Medicaid · Medicare · Private insurance +2 more

“Get help” calls our free helpline, not this facility.

7.0Very goodStartDrugRehab Score 7.0 out of 10
3.2Google11 reviews

CARF accredited

Setting
Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Intensive Outpatient
  • Outpatient
  • Medication-Assisted Treatment
  • +2 more

Payment accepted

Medicaid

“Get help” calls our free helpline, not this facility.

More options in Owensboro, KY

MAT Programs in other Kentucky cities

Frequently asked questions

How many mat programs are in Owensboro, KY?

We list 5 mat programs in Owensboro, KY, based on SAMHSA's FindTreatment.gov data (updated October 2026).

How do I choose the right program?

Look for state licensing and accreditation (The Joint Commission or CARF), the right level of care for your needs, evidence-based therapies, and insurance compatibility. Read our guide to choosing a rehab or call (833) 589-6933 to talk it through.

Will my insurance cover treatment?

Most private plans and Medicaid cover substance use treatment when it's medically necessary, but benefits vary by plan and network. Call (833) 589-6933 for a free, confidential benefits check.

Source: SAMHSA FindTreatment.gov, data updated October 2026. Listings are not endorsements.