We list 18 mat programs in Saint Louis, MO, based on SAMHSA's FindTreatment.gov data. Compare services, insurance accepted and accreditation, or call for free help choosing.
Medication-Assisted Treatment (MAT): the basics
Medication-assisted treatment (MAT) uses FDA-approved medications, usually alongside counseling, to treat opioid and alcohol use disorders. For opioids, the options are buprenorphine (including Suboxone), methadone and naltrexone. These medications ease cravings and withdrawal, help prevent a return to use and lower overdose risk. Search below to find MAT and Suboxone clinics near you. Read the full guide →
2026 rankings
Ranked by the StartDrugRehab Score: accreditation, levels of care, patient ratings and payment options. Featured or claimed status never affects rank. How we rank
Best for: Detox and residential careCARF
Why it made our list: CARF accredited; offers detox, residential care, PHP, and IOP; accepts private insurance, Medicaid, and Medicare.
Best for: Supervised detoxCARF
Why it made our list: CARF accredited; offers detox, PHP, IOP, and outpatient care; accepts private insurance, Medicaid, and self-pay.
Best for: Residential treatmentJoint Commission
Why it made our list: Joint Commission accredited; offers residential care, PHP, IOP, and outpatient care; accepts private insurance, Medicaid, and Medicare.
Best for: Supervised detoxCARF
Why it made our list: CARF accredited; offers detox, PHP, IOP, and outpatient care; accepts private insurance, Medicaid, and self-pay.
Best for: Intensive outpatient careJoint Commission
Why it made our list: Joint Commission accredited; offers PHP, IOP, outpatient care, and MAT; accepts private insurance, self-pay, and sliding-scale fees.
Best for: Intensive outpatient careCARF
Why it made our list: CARF accredited; offers PHP, IOP, outpatient care, and MAT; accepts private insurance, Medicaid, and Medicare.
Best for: Supervised detoxJoint Commission
Why it made our list: Joint Commission accredited; offers detox, IOP, outpatient care, and MAT; accepts Medicaid.
Best for: Supervised detoxCARF
Why it made our list: CARF accredited; offers detox, IOP, outpatient care, and MAT; accepts private insurance, Medicaid, and Medicare.
Best for: Intensive outpatient careCARF
Why it made our list: CARF accredited; offers IOP, outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Best for: Veterans (VA care)Joint Commission
Why it made our list: Joint Commission accredited; offers detox, outpatient care, MAT, and dual diagnosis care; accepts TRICARE.
Saint Louis, MO 63116
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63103
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay +1 more
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63136
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay +1 more
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63108
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63118
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63120
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay +1 more
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63103
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · State-funded
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63114
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +1 more
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63106
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63101
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63106
Joint Commission accredited
Levels of care
Payment accepted
TRICARE
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63125
Joint Commission accredited
Levels of care
Payment accepted
TRICARE
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63141
Joint Commission accredited
Levels of care
Payment accepted
Private insurance · Self-pay · Sliding scale
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63127
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63108
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63119
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63128
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +4 more
“Get help” calls our free helpline, not this facility.
Saint Louis, MO 63103
Joint Commission accredited
Levels of care
Payment accepted
TRICARE
“Get help” calls our free helpline, not this facility.
We list 18 mat programs in Saint Louis, MO, based on SAMHSA's FindTreatment.gov data (updated October 2026).
Look for state licensing and accreditation (The Joint Commission or CARF), the right level of care for your needs, evidence-based therapies, and insurance compatibility. Read our guide to choosing a rehab or call (833) 589-6933 to talk it through.
Most private plans and Medicaid cover substance use treatment when it's medically necessary, but benefits vary by plan and network. Call (833) 589-6933 for a free, confidential benefits check.
Source: SAMHSA FindTreatment.gov, data updated October 2026. Listings are not endorsements.
