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10 Best Dual Diagnosis Treatment Centers in Knoxville, TN (2026)

We list 17 dual diagnosis treatment centers in Knoxville, TN, based on SAMHSA's FindTreatment.gov data. Compare services, insurance accepted and accreditation, or call for free help choosing.

  • 17Treatment facilities
  • 3Offer detox
  • 4Inpatient / residential
  • 16Accept Medicaid

Dual Diagnosis: the basics

Dual diagnosis treatment is care for people who have both a substance use disorder and a mental health condition, such as depression, anxiety, PTSD or bipolar disorder. The best programs treat both conditions at the same time with one coordinated team, combining therapy, psychiatric care and, when needed, medication for addiction. Read the full guide →

2026 rankings

Top 10 dual diagnosis treatment centers in Knoxville, TN

Ranked by the StartDrugRehab Score: accreditation, levels of care, patient ratings and payment options. Featured or claimed status never affects rank. How we rank

  1. JourneyPure – Knoxville

    Knoxville, TN

    8.8ExcellentStartDrugRehab Score 8.8 out of 10
    4.9Google135 reviews

    Best for: Supervised detoxCARF

    Why it made our list: CARF accredited; offers detox, PHP, IOP, and outpatient care; accepts private insurance, Medicaid, and self-pay.

    View details
  2. Cedar Recovery – East Knoxville

    Knoxville, TN

    8.0ExcellentStartDrugRehab Score 8.0 out of 10
    4.9Google86 reviews

    Best for: Outpatient care with MATCARF

    Why it made our list: CARF accredited; offers outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.

    View details
  3. Helen Ross McNabb Center – CenterPointe

    Knoxville, TN

    7.5Very goodStartDrugRehab Score 7.5 out of 10
    3.6Google37 reviews

    Best for: Detox and residential careCARF

    Why it made our list: CARF accredited; offers detox, residential care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.

    View details
  4. Helen Ross McNabb – Knox County Children and Youth Center

    Knoxville, TN

    7.5Very goodStartDrugRehab Score 7.5 out of 10
    4.0Google10 reviews

    Best for: Intensive outpatient careCARF

    Why it made our list: CARF accredited; offers IOP, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.

    View details
  5. Peninsula Substance Abuse Services

    Knoxville, TN

    7.2Very goodStartDrugRehab Score 7.2 out of 10
    3.0Google31 reviews

    Best for: Intensive outpatient careJoint Commission

    Why it made our list: Joint Commission accredited; offers IOP, outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.

    View details
  6. River Valley Health – Formerly Cherokee Health Systems

    Knoxville, TN

    6.6GoodStartDrugRehab Score 6.6 out of 10
    4.6Google74 reviews

    Best for: Outpatient care with MAT

    Why it made our list: Offers outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.

    View details
  7. East TN Addiction Specialists

    Knoxville, TN

    6.6GoodStartDrugRehab Score 6.6 out of 10
    4.5Google80 reviews

    Best for: Outpatient care with MAT

    Why it made our list: Offers outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.

    View details
  8. Health Connect America

    Knoxville, TN

    6.0GoodStartDrugRehab Score 6.0 out of 10
    3.4Google10 reviews

    Best for: Intensive outpatient careCOA

    Why it made our list: COA accredited; offers IOP, outpatient care, and dual diagnosis care; accepts Medicaid and self-pay.

    View details
  9. Florence Crittenton Agency Inc

    Knoxville, TN

    5.6FairStartDrugRehab Score 5.6 out of 10
    3.0Google41 reviews

    Best for: Residential treatmentCOA

    Why it made our list: COA accredited; offers residential care and dual diagnosis care; accepts private insurance, Medicaid, and self-pay.

    View details
  10. EM Jellinek Center

    Knoxville, TN

    5.5FairStartDrugRehab Score 5.5 out of 10

    Best for: Residential treatment

    Why it made our list: Offers residential care and dual diagnosis care; accepts self-pay.

    View details

See the best rehab centers in Knoxville, TN →

All dual diagnosis treatment centers in Knoxville, TN

JourneyPure – Womens Center

Knoxville, TN 37920

8.1ExcellentStartDrugRehab Score 8.1 out of 10
4.7Google135 reviews

CARF accredited

Setting
In/Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Detox
  • Inpatient / Residential
  • Hospital Inpatient
  • +3 more

Payment accepted

Medicaid · Private insurance · Self-pay

“Get help” calls our free helpline, not this facility.

7.5Very goodStartDrugRehab Score 7.5 out of 10
3.6Google37 reviews

CARF accredited

Setting
In/Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Detox
  • Inpatient / Residential
  • Medication-Assisted Treatment
  • +2 more

Payment accepted

Medicaid · Medicare · Private insurance +3 more

“Get help” calls our free helpline, not this facility.

JourneyPure – Knoxville

Knoxville, TN 37919

8.8ExcellentStartDrugRehab Score 8.8 out of 10
4.9Google135 reviews

CARF accredited

Setting
In/Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Detox
  • Partial Hospitalization
  • Intensive Outpatient
  • +5 more

Payment accepted

Medicaid · Private insurance · Self-pay

“Get help” calls our free helpline, not this facility.

Cedar Recovery – East Knoxville

Knoxville, TN 37924

8.0ExcellentStartDrugRehab Score 8.0 out of 10
4.9Google86 reviews

CARF accredited

Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Medicare · Private insurance +2 more

“Get help” calls our free helpline, not this facility.

8.0ExcellentStartDrugRehab Score 8.0 out of 10
4.9Google63 reviews

CARF accredited

Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Medicare · Private insurance +2 more

“Get help” calls our free helpline, not this facility.

7.5Very goodStartDrugRehab Score 7.5 out of 10
4.0Google10 reviews

CARF accredited

Setting
Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Intensive Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Medicare · Private insurance +3 more

“Get help” calls our free helpline, not this facility.

7.5Very goodStartDrugRehab Score 7.5 out of 10

CARF accredited

Setting
Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Intensive Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Medicare · Private insurance +3 more

“Get help” calls our free helpline, not this facility.

7.2Very goodStartDrugRehab Score 7.2 out of 10
3.0Google31 reviews

Joint Commission accredited

Setting
Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Intensive Outpatient
  • Outpatient
  • Medication-Assisted Treatment
  • +2 more

Payment accepted

Medicaid · Medicare · Private insurance +3 more

“Get help” calls our free helpline, not this facility.

Florence Crittenton Agency Inc

Knoxville, TN 37909

5.6FairStartDrugRehab Score 5.6 out of 10
3.0Google41 reviews

COA accredited

Setting
In/Outpatient
Operator
Nonprofit
MAT
Not listed

Levels of care

  • Inpatient / Residential
  • Dual Diagnosis
  • Telehealth

Payment accepted

Medicaid · Private insurance · Self-pay

“Get help” calls our free helpline, not this facility.

East TN Addiction Specialists

Knoxville, TN 37923

6.6GoodStartDrugRehab Score 6.6 out of 10
4.5Google80 reviews
Setting
Outpatient
Operator
Private
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Medicare · Private insurance +2 more

“Get help” calls our free helpline, not this facility.

EM Jellinek Center

Knoxville, TN 37917

5.5FairStartDrugRehab Score 5.5 out of 10
Setting
Inpatient
Operator
Nonprofit
MAT
Not listed

Levels of care

  • Inpatient / Residential
  • Dual Diagnosis
  • Sober Living / Transitional Housing

Payment accepted

Self-pay · State-funded

“Get help” calls our free helpline, not this facility.

River Valley Health

Knoxville, TN 37917

6.5GoodStartDrugRehab Score 6.5 out of 10
4.5Google56 reviews
Setting
Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Medicare · Private insurance +4 more

“Get help” calls our free helpline, not this facility.

6.3GoodStartDrugRehab Score 6.3 out of 10
4.1Google90 reviews
Setting
Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Medicare · Private insurance +4 more

“Get help” calls our free helpline, not this facility.

6.5GoodStartDrugRehab Score 6.5 out of 10
4.5Google38 reviews
Setting
Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Medicare · Private insurance +4 more

“Get help” calls our free helpline, not this facility.

6.6GoodStartDrugRehab Score 6.6 out of 10
4.1Google362 reviews
Setting
Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Intensive Outpatient
  • Outpatient
  • Medication-Assisted Treatment
  • +2 more

Payment accepted

Medicaid · Medicare · Private insurance +4 more

“Get help” calls our free helpline, not this facility.

6.6GoodStartDrugRehab Score 6.6 out of 10
4.6Google74 reviews
Setting
Outpatient
Operator
Nonprofit
MAT
Offered

Levels of care

  • Outpatient
  • Medication-Assisted Treatment
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Medicare · Private insurance +4 more

“Get help” calls our free helpline, not this facility.

Health Connect America

Knoxville, TN 37921

6.0GoodStartDrugRehab Score 6.0 out of 10
3.4Google10 reviews

COA accredited

Setting
Outpatient
Operator
Private
MAT
Not listed

Levels of care

  • Intensive Outpatient
  • Outpatient
  • Dual Diagnosis
  • +1 more

Payment accepted

Medicaid · Self-pay · State-funded

“Get help” calls our free helpline, not this facility.

More options in Knoxville, TN

Dual Diagnosis Treatment Centers in other Tennessee cities

Frequently asked questions

How many dual diagnosis treatment centers are in Knoxville, TN?

We list 17 dual diagnosis treatment centers in Knoxville, TN, based on SAMHSA's FindTreatment.gov data (updated October 2026).

How do I choose the right program?

Look for state licensing and accreditation (The Joint Commission or CARF), the right level of care for your needs, evidence-based therapies, and insurance compatibility. Read our guide to choosing a rehab or call (833) 589-6933 to talk it through.

Will my insurance cover treatment?

Most private plans and Medicaid cover substance use treatment when it's medically necessary, but benefits vary by plan and network. Call (833) 589-6933 for a free, confidential benefits check.

Source: SAMHSA FindTreatment.gov, data updated October 2026. Listings are not endorsements.