We list 16 mat programs in Knoxville, TN, based on SAMHSA's FindTreatment.gov data. Compare services, insurance accepted and accreditation, or call for free help choosing.
Medication-Assisted Treatment (MAT): the basics
Medication-assisted treatment (MAT) uses FDA-approved medications, usually alongside counseling, to treat opioid and alcohol use disorders. For opioids, the options are buprenorphine (including Suboxone), methadone and naltrexone. These medications ease cravings and withdrawal, help prevent a return to use and lower overdose risk. Search below to find MAT and Suboxone clinics near you. Read the full guide →
2026 rankings
Ranked by the StartDrugRehab Score: accreditation, levels of care, patient ratings and payment options. Featured or claimed status never affects rank. How we rank
Best for: Supervised detoxCARF
Why it made our list: CARF accredited; offers detox, PHP, IOP, and outpatient care; accepts private insurance, Medicaid, and self-pay.
Best for: Outpatient care with MATCARF
Why it made our list: CARF accredited; offers outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Best for: Detox and residential careCARF
Why it made our list: CARF accredited; offers detox, residential care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Best for: Intensive outpatient careCARF
Why it made our list: CARF accredited; offers IOP, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Best for: Intensive outpatient careJoint Commission
Why it made our list: Joint Commission accredited; offers IOP, outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Best for: Outpatient care with MATCARFCOA
Why it made our list: CARF and COA accredited; offers MAT; accepts private insurance, Medicaid, and Medicare.
Best for: Methadone treatmentJoint Commission
Why it made our list: Joint Commission accredited; offers outpatient care and MAT; accepts private insurance, Medicaid, and Medicare.
Best for: Outpatient care with MAT
Why it made our list: Offers outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Best for: Outpatient care with MAT
Why it made our list: Offers outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Knoxville, TN 37920
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay
“Get help” calls our free helpline, not this facility.
Knoxville, TN 37921
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Knoxville, TN 37919
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay
“Get help” calls our free helpline, not this facility.
Knoxville, TN 37921
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Knoxville, TN 37924
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Knoxville, TN 37920
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Knoxville, TN 37921
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Knoxville, TN 37917
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Knoxville, TN 37909
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Knoxville, TN 37916
CARF · COA accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Knoxville, TN 37923
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Knoxville, TN 37917
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +4 more
“Get help” calls our free helpline, not this facility.
Knoxville, TN 37915
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +4 more
“Get help” calls our free helpline, not this facility.
Knoxville, TN 37921
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +4 more
“Get help” calls our free helpline, not this facility.
Knoxville, TN 37921
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +4 more
“Get help” calls our free helpline, not this facility.
Knoxville, TN 37919
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +4 more
“Get help” calls our free helpline, not this facility.
We list 16 mat programs in Knoxville, TN, based on SAMHSA's FindTreatment.gov data (updated October 2026).
Look for state licensing and accreditation (The Joint Commission or CARF), the right level of care for your needs, evidence-based therapies, and insurance compatibility. Read our guide to choosing a rehab or call (833) 589-6933 to talk it through.
Most private plans and Medicaid cover substance use treatment when it's medically necessary, but benefits vary by plan and network. Call (833) 589-6933 for a free, confidential benefits check.
Source: SAMHSA FindTreatment.gov, data updated October 2026. Listings are not endorsements.
