We list 4 methadone clinics in Mississippi, based on SAMHSA's FindTreatment.gov data, with the most in Jackson (1), Biloxi (1), and Walls (1). Compare services, insurance accepted and accreditation, or call for free help choosing.
Methadone Clinic (OTP): the basics
A methadone clinic, formally called an opioid treatment program (OTP), is a federally certified clinic that treats opioid use disorder with medication, mainly methadone. You visit to take a supervised dose and get counseling and medical care. Under 2024 federal rules, stable patients can earn take-home doses sooner. Search below to find methadone clinics near you. Read the full guide →
2026 rankings
Ranked by the StartDrugRehab Score: accreditation, levels of care, patient ratings and payment options. Featured or claimed status never affects rank. How we rank
Best for: Supervised detoxJoint CommissionCARF
Why it made our list: Joint Commission and CARF accredited; offers detox, outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Best for: Supervised detoxJoint Commission
Why it made our list: Joint Commission accredited; offers detox, PHP, IOP, and outpatient care; accepts private insurance, Medicaid, and Medicare.
Best for: Supervised detoxCARF
Why it made our list: CARF accredited; offers detox, outpatient care, and MAT; accepts private insurance, Medicaid, and Medicare.
Best for: Methadone treatmentCARF
Why it made our list: CARF accredited; offers IOP, outpatient care, and MAT; accepts private insurance, Medicaid, and Medicare.
Meridian, MS 39301
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Joint Commission · CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Biloxi, MS 39531
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +1 more
“Get help” calls our free helpline, not this facility.
We list 4 methadone clinics in Mississippi, based on SAMHSA's FindTreatment.gov data (updated October 2026).
The most listings are in Jackson (1), Biloxi (1), and Walls (1).
Look for state licensing and accreditation (The Joint Commission or CARF), the right level of care for your needs, evidence-based therapies, and insurance compatibility. Read our guide to choosing a rehab or call (833) 589-6933 to talk it through.
Most private plans and Medicaid cover substance use treatment when it's medically necessary, but benefits vary by plan and network. Call (833) 589-6933 for a free, confidential benefits check.
Source: SAMHSA FindTreatment.gov, data updated October 2026. Listings are not endorsements.
