We list 71 mat programs in Mississippi, based on SAMHSA's FindTreatment.gov data, with the most in Jackson (6), Tupelo (4), and Meridian (3). Compare services, insurance accepted and accreditation, or call for free help choosing.
Medication-Assisted Treatment (MAT): the basics
Medication-assisted treatment (MAT) uses FDA-approved medications, usually alongside counseling, to treat opioid and alcohol use disorders. For opioids, the options are buprenorphine (including Suboxone), methadone and naltrexone. These medications ease cravings and withdrawal, help prevent a return to use and lower overdose risk. Search below to find MAT and Suboxone clinics near you. Read the full guide →
2026 rankings
Ranked by the StartDrugRehab Score: accreditation, levels of care, patient ratings and payment options. Featured or claimed status never affects rank. How we rank
Best for: Private-pay residential careJoint Commission
Why it made our list: Joint Commission accredited; offers detox, residential care, PHP, and IOP; accepts private insurance, TRICARE, and self-pay.
Best for: Detox and residential careJoint Commission
Why it made our list: Joint Commission accredited; offers detox, residential care, PHP, and IOP; accepts private insurance, Medicaid, and TRICARE.
Best for: Supervised detoxJoint CommissionCARF
Why it made our list: Joint Commission and CARF accredited; offers detox, outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Best for: Supervised detoxJoint Commission
Why it made our list: Joint Commission accredited; offers detox, PHP, IOP, and outpatient care; accepts private insurance, Medicaid, and Medicare.
Best for: Intensive outpatient careJoint Commission
Why it made our list: Joint Commission accredited; offers IOP, outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Best for: Veterans (VA care)Joint CommissionCARF
Why it made our list: Joint Commission and CARF accredited; offers detox, residential care, IOP, and outpatient care; accepts private insurance, Medicaid, and Medicare.
Best for: Supervised detoxJoint Commission
Why it made our list: Joint Commission accredited; offers detox, IOP, outpatient care, and MAT; accepts private insurance, Medicaid, and Medicare.
Best for: Intensive outpatient careJoint Commission
Why it made our list: Joint Commission accredited; offers PHP, IOP, MAT, and dual diagnosis care; accepts private insurance and self-pay.
Best for: Private-pay residential careJoint Commission
Why it made our list: Joint Commission accredited; offers detox, residential care, MAT, and dual diagnosis care; accepts private insurance and self-pay.
Best for: Detox and residential careCARF
Why it made our list: CARF accredited; offers detox, residential care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Vicksburg, MS 39180
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Private insurance · TRICARE +1 more
“Get help” calls our free helpline, not this facility.
Jackson, MS 39216
Joint Commission · CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Biloxi, MS 39532
Joint Commission accredited
Levels of care
Payment accepted
Private insurance · TRICARE · Self-pay +1 more
“Get help” calls our free helpline, not this facility.
Oxford, MS 38655
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +4 more
“Get help” calls our free helpline, not this facility.
Meridian, MS 39301
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Etta, MS 38627
Joint Commission accredited
Levels of care
Payment accepted
Private insurance · Self-pay
“Get help” calls our free helpline, not this facility.
Brandon, MS 39047
Joint Commission accredited
Levels of care
Payment accepted
Private insurance · TRICARE · Self-pay
“Get help” calls our free helpline, not this facility.
Joint Commission · CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Whitfield, MS 39193
Joint Commission accredited
Levels of care
Payment accepted
Private insurance
“Get help” calls our free helpline, not this facility.
Columbus, MS 39701
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Laurel, MS 39440
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Moselle, MS 39459
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · TRICARE +3 more
“Get help” calls our free helpline, not this facility.
Gulfport, MS 39503
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · TRICARE +3 more
“Get help” calls our free helpline, not this facility.
Greenwood, MS 38930
Levels of care
Payment accepted
Self-pay · Sliding scale
“Get help” calls our free helpline, not this facility.
Byram, MS 39272
CARF accredited
Levels of care
Payment accepted
Self-pay · State-funded
“Get help” calls our free helpline, not this facility.
Hattiesburg, MS 39401
CARF accredited
Levels of care
Payment accepted
Self-pay
“Get help” calls our free helpline, not this facility.
Tupelo, MS 38804
Levels of care
Payment accepted
Medicaid · Self-pay · Sliding scale +1 more
“Get help” calls our free helpline, not this facility.
Jackson, MS 39211
Joint Commission accredited
Levels of care
Payment accepted
Private insurance · Self-pay
“Get help” calls our free helpline, not this facility.
Biloxi, MS 39531
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +1 more
“Get help” calls our free helpline, not this facility.
Ridgeland, MS 39157
Joint Commission accredited
Levels of care
Payment accepted
Private insurance · TRICARE · Self-pay
“Get help” calls our free helpline, not this facility.
Tupelo, MS 38801
CARF accredited
Levels of care
Payment accepted
Private insurance · Self-pay
“Get help” calls our free helpline, not this facility.
Tutwiler, MS 38963
Levels of care
Payment accepted
Self-pay · Sliding scale · State-funded
“Get help” calls our free helpline, not this facility.
Oxford, MS 38655
Joint Commission accredited
Levels of care
Payment accepted
Private insurance · Self-pay
“Get help” calls our free helpline, not this facility.
Flowood, MS 39232
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Collins, MS 39428
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +4 more
“Get help” calls our free helpline, not this facility.
Purvis, MS 39475
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +4 more
“Get help” calls our free helpline, not this facility.
Summit, MS 39666
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +4 more
“Get help” calls our free helpline, not this facility.
Hazlehurst, MS 39083
Levels of care
Payment accepted
Medicaid · Self-pay · State-funded
“Get help” calls our free helpline, not this facility.
Mendenhall, MS 39114
Levels of care
Payment accepted
Medicaid · Self-pay · State-funded
“Get help” calls our free helpline, not this facility.
We list 71 mat programs in Mississippi, based on SAMHSA's FindTreatment.gov data (updated October 2026).
The most listings are in Jackson (6), Tupelo (4), and Meridian (3).
Look for state licensing and accreditation (The Joint Commission or CARF), the right level of care for your needs, evidence-based therapies, and insurance compatibility. Read our guide to choosing a rehab or call (833) 589-6933 to talk it through.
Most private plans and Medicaid cover substance use treatment when it's medically necessary, but benefits vary by plan and network. Call (833) 589-6933 for a free, confidential benefits check.
Source: SAMHSA FindTreatment.gov, data updated October 2026. Listings are not endorsements.
