We list 1 methadone clinics in South Dakota, based on SAMHSA's FindTreatment.gov data, with the most in Sioux Falls (1). Compare services, insurance accepted and accreditation, or call for free help choosing.
Methadone Clinic (OTP): the basics
A methadone clinic, formally called an opioid treatment program (OTP), is a federally certified clinic that treats opioid use disorder with medication, mainly methadone. You visit to take a supervised dose and get counseling and medical care. Under 2024 federal rules, stable patients can earn take-home doses sooner. Search below to find methadone clinics near you. Read the full guide →
Sioux Falls, SD 57104
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
We list 1 methadone clinics in South Dakota, based on SAMHSA's FindTreatment.gov data (updated October 2026).
The most listings are in Sioux Falls (1).
Look for state licensing and accreditation (The Joint Commission or CARF), the right level of care for your needs, evidence-based therapies, and insurance compatibility. Read our guide to choosing a rehab or call (833) 589-6933 to talk it through.
Most private plans and Medicaid cover substance use treatment when it's medically necessary, but benefits vary by plan and network. Call (833) 589-6933 for a free, confidential benefits check.
Source: SAMHSA FindTreatment.gov, data updated October 2026. Listings are not endorsements.
