We list 18 detox centers in South Carolina, based on SAMHSA's FindTreatment.gov data, with the most in Columbia (3), Greenville (3), and North Charleston (2). Compare services, insurance accepted and accreditation, or call for free help choosing.
Detox: the basics
Detox centers provide medically supervised withdrawal management, helping you safely stop alcohol or drugs while trained staff treat withdrawal symptoms. Most stays last several days to about two weeks, depending on the substance and your health. Search below for licensed detox centers near you, and plan for ongoing care, since detox is the first step in treatment, not a cure. Read the full guide →
2026 rankings
Ranked by the StartDrugRehab Score: accreditation, levels of care, patient ratings and payment options. Featured or claimed status never affects rank. How we rank
Best for: Private-pay residential careJoint CommissionCOA
Why it made our list: Joint Commission and COA accredited; offers detox, residential care, PHP, and IOP; accepts private insurance and self-pay.
Best for: Supervised detoxJoint Commission
Why it made our list: Joint Commission accredited; offers detox, PHP, IOP, and outpatient care; accepts private insurance, TRICARE, and self-pay.
Best for: Supervised detoxJoint Commission
Why it made our list: Joint Commission accredited; offers detox, outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Best for: Supervised detoxJoint Commission
Why it made our list: Joint Commission accredited; offers detox, PHP, IOP, and outpatient care; accepts private insurance and self-pay.
Best for: Supervised detoxJoint Commission
Why it made our list: Joint Commission accredited; offers detox, PHP, IOP, and MAT; accepts private insurance, Medicare, and TRICARE.
Best for: Supervised detoxCARF
Why it made our list: CARF accredited; offers detox, outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Best for: Supervised detoxJoint Commission
Why it made our list: Joint Commission accredited; offers detox, outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Best for: Private-pay residential careJoint Commission
Why it made our list: Joint Commission accredited; offers detox, residential care, MAT, and dual diagnosis care; accepts private insurance, TRICARE, and self-pay.
Best for: Supervised detoxJoint Commission
Why it made our list: Joint Commission accredited; offers detox, PHP, IOP, and MAT; accepts private insurance, Medicaid, and Medicare.
Best for: Detox and residential careCARF
Why it made our list: CARF accredited; offers detox, residential care, IOP, and outpatient care; accepts private insurance, Medicaid, and Medicare.
Rock Hill, SC 29732
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay +2 more
“Get help” calls our free helpline, not this facility.
Columbia, SC 29203
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Greenville, SC 29615
Joint Commission · COA accredited
Levels of care
Payment accepted
Private insurance · Self-pay
“Get help” calls our free helpline, not this facility.
Chesnee, SC 29323
Joint Commission accredited
Levels of care
Payment accepted
Private insurance · TRICARE · Self-pay +1 more
“Get help” calls our free helpline, not this facility.
North Charleston, SC 29405
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Columbia, SC 29203
CARF accredited
Levels of care
Payment accepted
Private insurance · TRICARE · Self-pay
“Get help” calls our free helpline, not this facility.
Simpsonville, SC 29680
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Aiken, SC 29801
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
North Charleston, SC 29405
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Greer, SC 29650
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Myrtle Beach, SC 29577
Joint Commission accredited
Levels of care
Payment accepted
Private insurance · Self-pay
“Get help” calls our free helpline, not this facility.
Greenville, SC 29607
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · TRICARE +3 more
“Get help” calls our free helpline, not this facility.
Bluffton, SC 29910
Joint Commission accredited
Levels of care
Payment accepted
Private insurance · TRICARE · Self-pay
“Get help” calls our free helpline, not this facility.
West Columbia, SC 29169
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · TRICARE +2 more
“Get help” calls our free helpline, not this facility.
Myrtle Beach, SC 29577
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Columbia, SC 29210
Joint Commission accredited
Levels of care
Payment accepted
Medicare · Private insurance · TRICARE +1 more
“Get help” calls our free helpline, not this facility.
Orangeburg, SC 29115
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Private insurance · TRICARE +3 more
“Get help” calls our free helpline, not this facility.
Greenville, SC 29605
Levels of care
Payment accepted
Private insurance · Self-pay
“Get help” calls our free helpline, not this facility.
We list 18 detox centers in South Carolina, based on SAMHSA's FindTreatment.gov data (updated October 2026).
The most listings are in Columbia (3), Greenville (3), and North Charleston (2).
Look for state licensing and accreditation (The Joint Commission or CARF), the right level of care for your needs, evidence-based therapies, and insurance compatibility. Read our guide to choosing a rehab or call (833) 589-6933 to talk it through.
Most private plans and Medicaid cover substance use treatment when it's medically necessary, but benefits vary by plan and network. Call (833) 589-6933 for a free, confidential benefits check.
Source: SAMHSA FindTreatment.gov, data updated October 2026. Listings are not endorsements.
