We list 70 dual diagnosis treatment centers in South Carolina, based on SAMHSA's FindTreatment.gov data, with the most in Florence (7), Columbia (5), and Greenville (4). Compare services, insurance accepted and accreditation, or call for free help choosing.
Dual Diagnosis: the basics
Dual diagnosis treatment is care for people who have both a substance use disorder and a mental health condition, such as depression, anxiety, PTSD or bipolar disorder. The best programs treat both conditions at the same time with one coordinated team, combining therapy, psychiatric care and, when needed, medication for addiction. Read the full guide →
2026 rankings
Ranked by the StartDrugRehab Score: accreditation, levels of care, patient ratings and payment options. Featured or claimed status never affects rank. How we rank
Best for: Supervised detoxJoint Commission
Why it made our list: Joint Commission accredited; offers detox, PHP, IOP, and outpatient care; accepts private insurance, TRICARE, and self-pay.
Best for: Supervised detoxJoint Commission
Why it made our list: Joint Commission accredited; offers detox, outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Best for: Supervised detoxJoint Commission
Why it made our list: Joint Commission accredited; offers detox, PHP, IOP, and outpatient care; accepts private insurance and self-pay.
Best for: Residential treatmentCARF
Why it made our list: CARF accredited; offers residential care, PHP, IOP, and outpatient care; accepts private insurance, Medicaid, and TRICARE.
Best for: Supervised detoxJoint Commission
Why it made our list: Joint Commission accredited; offers detox, PHP, IOP, and MAT; accepts private insurance, Medicare, and TRICARE.
Best for: Supervised detoxCARF
Why it made our list: CARF accredited; offers detox, outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Best for: Intensive outpatient careJoint Commission
Why it made our list: Joint Commission accredited; offers PHP, IOP, MAT, and dual diagnosis care; accepts private insurance, TRICARE, and self-pay.
Best for: Intensive outpatient careJoint Commission
Why it made our list: Joint Commission accredited; offers PHP, IOP, outpatient care, and MAT; accepts private insurance, TRICARE, and self-pay.
Best for: Supervised detoxJoint Commission
Why it made our list: Joint Commission accredited; offers detox, outpatient care, MAT, and dual diagnosis care; accepts private insurance, Medicaid, and Medicare.
Best for: Private-pay residential careJoint Commission
Why it made our list: Joint Commission accredited; offers detox, residential care, MAT, and dual diagnosis care; accepts private insurance, TRICARE, and self-pay.
Rock Hill, SC 29732
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay +2 more
“Get help” calls our free helpline, not this facility.
Columbia, SC 29203
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Chesnee, SC 29323
Joint Commission accredited
Levels of care
Payment accepted
Private insurance · TRICARE · Self-pay +1 more
“Get help” calls our free helpline, not this facility.
Columbia, SC 29203
CARF accredited
Levels of care
Payment accepted
Private insurance · TRICARE · Self-pay
“Get help” calls our free helpline, not this facility.
Simpsonville, SC 29680
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
North Charleston, SC 29405
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Greer, SC 29650
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Myrtle Beach, SC 29577
Joint Commission accredited
Levels of care
Payment accepted
Private insurance · Self-pay
“Get help” calls our free helpline, not this facility.
Greenville, SC 29611
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · TRICARE +3 more
“Get help” calls our free helpline, not this facility.
Bluffton, SC 29910
Joint Commission accredited
Levels of care
Payment accepted
Private insurance · TRICARE · Self-pay
“Get help” calls our free helpline, not this facility.
Florence, SC 29501
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay +1 more
“Get help” calls our free helpline, not this facility.
West Columbia, SC 29169
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · TRICARE +2 more
“Get help” calls our free helpline, not this facility.
Spartanburg, SC 29307
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay +1 more
“Get help” calls our free helpline, not this facility.
Myrtle Beach, SC 29577
CARF accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +2 more
“Get help” calls our free helpline, not this facility.
Columbia, SC 29210
Joint Commission accredited
Levels of care
Payment accepted
Medicare · Private insurance · TRICARE +1 more
“Get help” calls our free helpline, not this facility.
Orangeburg, SC 29115
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Private insurance · TRICARE +3 more
“Get help” calls our free helpline, not this facility.
Jacksonboro, SC 29452
Joint Commission accredited
Levels of care
Payment accepted
Private insurance · Self-pay
“Get help” calls our free helpline, not this facility.
Florence, SC 29501
Joint Commission accredited
Levels of care
Payment accepted
Private insurance · TRICARE · Self-pay
“Get help” calls our free helpline, not this facility.
North Charleston, SC 29405
Joint Commission accredited
Levels of care
Payment accepted
Private insurance · TRICARE · Self-pay +2 more
“Get help” calls our free helpline, not this facility.
Aiken, SC 29801
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay +2 more
“Get help” calls our free helpline, not this facility.
Chesterfield, SC 29709
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay +2 more
“Get help” calls our free helpline, not this facility.
Camden, SC 29020
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay +2 more
“Get help” calls our free helpline, not this facility.
Barnwell, SC 29812
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay +1 more
“Get help” calls our free helpline, not this facility.
Easley, SC 29640
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · TRICARE +3 more
“Get help” calls our free helpline, not this facility.
Spartanburg, SC 29303
Joint Commission accredited
Levels of care
Payment accepted
Medicaid · Medicare · Private insurance +3 more
“Get help” calls our free helpline, not this facility.
Gaffney, SC 29341
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · TRICARE +3 more
“Get help” calls our free helpline, not this facility.
Florence, SC 29501
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay +1 more
“Get help” calls our free helpline, not this facility.
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay +2 more
“Get help” calls our free helpline, not this facility.
Walterboro, SC 29488
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay +2 more
“Get help” calls our free helpline, not this facility.
Abbeville, SC 29620
CARF accredited
Levels of care
Payment accepted
Medicaid · Private insurance · Self-pay +1 more
“Get help” calls our free helpline, not this facility.
We list 70 dual diagnosis treatment centers in South Carolina, based on SAMHSA's FindTreatment.gov data (updated October 2026).
The most listings are in Florence (7), Columbia (5), and Greenville (4).
Look for state licensing and accreditation (The Joint Commission or CARF), the right level of care for your needs, evidence-based therapies, and insurance compatibility. Read our guide to choosing a rehab or call (833) 589-6933 to talk it through.
Most private plans and Medicaid cover substance use treatment when it's medically necessary, but benefits vary by plan and network. Call (833) 589-6933 for a free, confidential benefits check.
Source: SAMHSA FindTreatment.gov, data updated October 2026. Listings are not endorsements.
