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4 Best Mental Health Treatment Centers in South Carolina (2026)

We list 4 mental health treatment centers in South Carolina, based on SAMHSA's FindTreatment.gov data, with the most in West Columbia (1), Greenville (1), and Walterboro (1). Compare services, insurance accepted and accreditation, or call for free help choosing.

  • 4Treatment facilities
  • 0Offer detox
  • 0Inpatient / residential
  • 0Accept Medicaid

Mental Health Treatment: the basics

Residential and inpatient mental health treatment centers provide 24-hour care for conditions such as depression, anxiety, bipolar disorder, PTSD and psychosis when outpatient therapy is not enough. Partial hospitalization (PHP) offers full-day treatment while you sleep at home. Read the full guide →

2026 rankings

Top 4 mental health treatment centers in South Carolina

Ranked by the StartDrugRehab Score: accreditation, levels of care, patient ratings and payment options. Featured or claimed status never affects rank. How we rank

  1. Colleton Medical Center

    Walterboro, SC

    4.4Google1,207 reviews

    Best for: Outpatient care

    Why it made our list: Accepts private insurance, Medicaid, and Medicare.

    View details
  2. Windwood Farm Home for Children

    Awendaw, SC

    4.9Google17 reviews

    Best for: Outpatient care

    Why it made our list: Accepts Medicaid.

    View details
  3. Marshall I Pickens Hospital – Greenville Memorial Medical Campus

    Greenville, SC

    2.6Google79 reviews

    Best for: Outpatient care

    Why it made our list: Accepts private insurance, Medicaid, and Medicare.

    View details
  4. Three Rivers Residential Treatment Services

    West Columbia, SC

    2.0Google82 reviews

    Best for: Outpatient care

    Why it made our list: Accepts private insurance, Medicaid, and TRICARE.

    View details

See the best rehab centers in South Carolina →

Cities with mental health treatment centers in SC

All mental health treatment centers in South Carolina

Colleton Medical Center

Walterboro, SC 29488

4.4Google1,207 reviews
Setting
—
Operator
Private
MAT
Not listed

Levels of care

  • Mental Health Treatment

Payment accepted

Medicaid · Medicare · Private insurance +2 more

“Get help” calls our free helpline, not this facility.

2.0Google82 reviews
Setting
—
Operator
Private
MAT
Not listed

Levels of care

  • Mental Health Treatment

Payment accepted

Medicaid · Private insurance · TRICARE +1 more

“Get help” calls our free helpline, not this facility.

4.9Google17 reviews
Setting
—
Operator
Nonprofit
MAT
Not listed

Levels of care

  • Mental Health Treatment

Payment accepted

Medicaid

“Get help” calls our free helpline, not this facility.

More options in South Carolina

Mental Health Treatment Centers in other states

Frequently asked questions

How many mental health treatment centers are in South Carolina?

We list 4 mental health treatment centers in South Carolina, based on SAMHSA's FindTreatment.gov data (updated October 2026).

Which South Carolina cities have the most mental health treatment centers?

The most listings are in West Columbia (1), Greenville (1), and Walterboro (1).

How do I choose the right program?

Look for state licensing and accreditation (The Joint Commission or CARF), the right level of care for your needs, evidence-based therapies, and insurance compatibility. Read our guide to choosing a rehab or call (833) 589-6933 to talk it through.

Will my insurance cover treatment?

Most private plans and Medicaid cover substance use treatment when it's medically necessary, but benefits vary by plan and network. Call (833) 589-6933 for a free, confidential benefits check.

Source: SAMHSA FindTreatment.gov, data updated October 2026. Listings are not endorsements.